We designed and validated a specific iDScore for the differentiation to atypical nevi (AN) from early melanomas (EM) of all body sites (excluding face, palms and plants). (1) Few relevant clinical-personal data were selected and coded according to a specific risk progression scale, that are: age (4 age range groups), lesions diameter (3 diamter groups) and body site (14 sites grouped according to a specifically developed sun-exposure based classification). The risk scale range was 0-16, so distributed: S=0-3: no risk 5; S=4-5: very low risk; S=6-7: low risk; S=8-10: moderate risk; S=11-13: high risk; S=14-16: very high risk. Corresponding managment suggestion are proposed to these 6 risk ranges: no follow-up/long follow-up/medium follow-up/short follow-up/very short follow-up/immediate excision.(1)
This checklist was further validated in a large multicentric dataset of lesion in a teledermatology setting, and compared with intuitive diagnosis based on pattern analysis, the ABCD rule and the 7-point checklist: the diagnostic accuracy reached was higher than the other methods for all tested lesions (~1000). Dermatologists of all experience in dermoscopy degree showed to benefit from the application of the iDScore algorithm, including: skill level I (<1 year-experience), skill level II (1-4 year-experience), skill level III (6-8 year-experience), skill level IV (>8 year-experience).(2)
Click here to proceed to the archived iDScore Body lesions 2018 project site (restricted access).
We here aim to extend the number of clinical-personal data to be evaluated along with the iDSCore 2018 body lesion, in order to increase the diagnostic accuracy of the method itself.
The list of clinical-personal data to be evaluated for the the iDSCore 2020-body lesion include:
Sex
Age (years)
Diameter (mm)
Phototype (I/II/IIII/IV/V/VI)
Personal history of melanoma
Family history of melanoma – 1st degree relative
Pheomelanine
Blond hair
Green/light-blue/blue eyes
Positive history of sunburns in childhood (<14 years)
Nevi on the right arm ≥ 11
Smoke
Beside the histological diangosis of AN / EM, some histologic parameters will be also evlauted, suc has:
Ulceration
Thickness (mm)
Mythoses (/mm2) regression
Lymphocytic infiltrate
Tognetti L, Cevenini G, Moscarella E, Cinotti E, Farnetani F, Mahlvey J, Perrot JL, Longo C, Pellacani G, Argenziano G, Fimiani M, Rubegni P. An integrated clinical-dermoscopic risk scoring system for the differentiation between early melanoma and atypical nevi: the iDScore. J Eur Acad Dermatol Venereol. 2018 Dec;32(12):2162-2170. DOI: 10.1111/jdv.15106. PMID: 29888421.
Tognetti L, Cevenini G, Moscarella E, Cinotti E, Farnetani F, Lallas A, Tiodorovic D, Carrera C, Puig S, Perrot JL, Longo C, Argenziano G, Pellacani G, Smargiassi E, Cataldo G, Cartocci A, Balistreri A, Rubegni P. Validation of an integrated dermoscopic scoring method in an European teledermoscopy web platform: the iDScore project for early detection of melanoma. J Eur Acad Dermatol Venereol 2019. DOI: 10.1111/jdv.15923. PMID: 31465600.
Tognetti L, Cartocci A, Balistreri A, Cataldo G, Cinotti E, Moscarella E, Farnetani F, Lallas A, Tiodorovic D, Carrera C, Longo C, Puig S, Perrot JL, Argenziano G, Pellacani G, Rubegni P, Cevenini G. The Comparative Use of Multiple Electronic Devices in the Teledermoscopic Diagnosis of Early Melanoma. Telemed J E Health. 2020 Aug 14. Epub ahead of print. DOI: 10.1089/tmj.2020.0057. PMID: 32799628.
Tognetti L, Cartocci A, Cinotti E, Moscarella E, Farnetani F, Lallas A, Tiodorovic D, Carrera C, Longo C, Puig S, Perrot JL, Argenziano G, Pellacani G, Cataldo G, Balistreri A, Cevenini G, Rubegni P. The impact of anatomical location and sun exposure on the dermoscopic recognition of atypical nevi and early melanomas: usefulness of an integrated clinical-dermoscopic method (iDScore). J Eur Acad Dermatol Venereol. 2020 Aug 2. Epub ahead of print. DOI: 10.1111/jdv.16847. PMID: 32743829.
Moscarella E, Pasquali P, Cinotti E, Tognetti L, Argenziano G, Rubegni P. A survey on teledermatology use and doctors' perception in times of COVID-19. J Eur Acad Dermatol Venereol. 2020 Aug 3. Epub ahead of print. DOI: 10.1111/jdv.16843. PMID: 32745276; PMCID: PMC7436459.